BDBM98937 US8497265, 349

SMILES: OCC1CCN(CC1)c1ncc(N2CCCCC2)c(OC2CN(C2)c2ccc3ccccc3n2)n1

InChI Key: InChIKey=MCYVOCMLEVOMLL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98937   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM98937 (US8497265, 349) Show SMILES OCC1CCN(CC1)c1ncc(N2CCCCC2)c(OC2CN(C2)c2ccc3ccccc3n2)n1 Show InChI InChI=1S/C27H34N6O2/c34-19-20-10-14-32(15-11-20)27-28-16-24(31-12-4-1-5-13-31)26(30-27)35-22-17-33(18-22)25-9-8-21-6-2-3-7-23(21)29-25/h2-3,6-9,16,20,22,34H,1,4-5,10-15,17-19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18.4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).				US Patent US8497265 (2013) BindingDB Entry DOI: 10.7270/Q2VD6X39
					More data for this Ligand-Target Pair