BDBM98970 US8497265, 426

SMILES: CC(=O)c1cccc(c1)-c1nccnc1OC1CN(C1)c1ccc2ccccc2n1

InChI Key: InChIKey=DVDRDHOYLRCPIQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM98970 (US8497265, 426) Show SMILES CC(=O)c1cccc(c1)-c1nccnc1OC1CN(C1)c1ccc2ccccc2n1 Show InChI InChI=1S/C24H20N4O2/c1-16(29)18-6-4-7-19(13-18)23-24(26-12-11-25-23)30-20-14-28(15-20)22-10-9-17-5-2-3-8-21(17)27-22/h2-13,20H,14-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11.2	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).				US Patent US8497265 (2013) BindingDB Entry DOI: 10.7270/Q2VD6X39
					More data for this Ligand-Target Pair