BDBM98993 US8497265, 449

SMILES: Clc1ccc(cn1)-c1nccnc1OC1CN(C1)c1ccc2ccccc2n1

InChI Key: InChIKey=IWQSTQYRJYRZCJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM98993 (US8497265, 449) Show SMILES Clc1ccc(cn1)-c1nccnc1OC1CN(C1)c1ccc2ccccc2n1 Show InChI InChI=1S/C21H16ClN5O/c22-18-7-5-15(11-25-18)20-21(24-10-9-23-20)28-16-12-27(13-16)19-8-6-14-3-1-2-4-17(14)26-19/h1-11,16H,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).				US Patent US8497265 (2013) BindingDB Entry DOI: 10.7270/Q2VD6X39
					More data for this Ligand-Target Pair