BDBM99009 US8497265, 465

SMILES: Cc1cc(ccn1)-c1cnc(nc1OC1CN(C1)c1ccc2ccccc2n1)N1CCC(CO)CC1

InChI Key: InChIKey=QKMOMGFVPAXGKE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM99009 (US8497265, 465) Show SMILES Cc1cc(ccn1)-c1cnc(nc1OC1CN(C1)c1ccc2ccccc2n1)N1CCC(CO)CC1 Show InChI InChI=1S/C28H30N6O2/c1-19-14-22(8-11-29-19)24-15-30-28(33-12-9-20(18-35)10-13-33)32-27(24)36-23-16-34(17-23)26-7-6-21-4-2-3-5-25(21)31-26/h2-8,11,14-15,20,23,35H,9-10,12-13,16-18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).				US Patent US8497265 (2013) BindingDB Entry DOI: 10.7270/Q2VD6X39
					More data for this Ligand-Target Pair