BDBM99025 US8497265, 481

SMILES: OCc1ccc(cc1)-c1nccc(OC2CN(C2)c2ccc3ccccc3n2)n1

InChI Key: InChIKey=AKJQZEBMCHNPKX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM99025 (US8497265, 481) Show SMILES OCc1ccc(cc1)-c1nccc(OC2CN(C2)c2ccc3ccccc3n2)n1 Show InChI InChI=1S/C23H20N4O2/c28-15-16-5-7-18(8-6-16)23-24-12-11-22(26-23)29-19-13-27(14-19)21-10-9-17-3-1-2-4-20(17)25-21/h1-12,19,28H,13-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.45	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).				US Patent US8497265 (2013) BindingDB Entry DOI: 10.7270/Q2VD6X39
					More data for this Ligand-Target Pair