BDBM99044 US8497265, 684

SMILES: CC(=O)N1CCCC(C1)c1cccnc1OC1CN(C1)C(=O)c1nc2ccccc2[nH]1

InChI Key: InChIKey=QCXRRTPEWMJYEZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99044   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM99044 (US8497265, 684) Show SMILES CC(=O)N1CCCC(C1)c1cccnc1OC1CN(C1)C(=O)c1nc2ccccc2[nH]1 Show InChI InChI=1S/C23H25N5O3/c1-15(29)27-11-5-6-16(12-27)18-7-4-10-24-22(18)31-17-13-28(14-17)23(30)21-25-19-8-2-3-9-20(19)26-21/h2-4,7-10,16-17H,5-6,11-14H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.47	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).				US Patent US8497265 (2013) BindingDB Entry DOI: 10.7270/Q2VD6X39
					More data for this Ligand-Target Pair