BDBM99048 US8497265, 688

SMILES: CC(=O)N1CCC(CC1)c1cnc(nc1OC1CN(C1)c1ccc2ccccc2n1)N1CCC(CO)CC1

InChI Key: InChIKey=KDRXVQBBOJZBQW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99048   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM99048 (US8497265, 688) Show SMILES CC(=O)N1CCC(CC1)c1cnc(nc1OC1CN(C1)c1ccc2ccccc2n1)N1CCC(CO)CC1 Show InChI InChI=1S/C29H36N6O3/c1-20(37)33-14-10-22(11-15-33)25-16-30-29(34-12-8-21(19-36)9-13-34)32-28(25)38-24-17-35(18-24)27-7-6-23-4-2-3-5-26(23)31-27/h2-7,16,21-22,24,36H,8-15,17-19H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).				US Patent US8497265 (2013) BindingDB Entry DOI: 10.7270/Q2VD6X39
					More data for this Ligand-Target Pair