BDBM99050 US8497265, 734

SMILES: C1C(CN1c1ccc2ccccc2n1)Oc1ncccc1N1CCOCC1

InChI Key: InChIKey=QRBFEDYENCUANS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99050   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM99050 (US8497265, 734) Show SMILES C1C(CN1c1ccc2ccccc2n1)Oc1ncccc1N1CCOCC1 Show InChI InChI=1S/C21H22N4O2/c1-2-5-18-16(4-1)7-8-20(23-18)25-14-17(15-25)27-21-19(6-3-9-22-21)24-10-12-26-13-11-24/h1-9,17H,10-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).				US Patent US8497265 (2013) BindingDB Entry DOI: 10.7270/Q2VD6X39
					More data for this Ligand-Target Pair