BDBM99211 US8497368, 1::US8497368, 17::US8497368, 18

SMILES: CC(=NNC(N)=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1

InChI Key: InChIKey=MKXUOJJCQVPIMD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 99211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM99211 (US8497368, 1 | US8497368, 17 | US8497368, 18) Show SMILES CC(=NNC(N)=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:2.2| Show InChI InChI=1S/C19H16FN7O/c1-11(24-25-19(21)28)16-4-5-18-23-10-14(27(18)26-16)8-13-7-12-3-2-6-22-17(12)9-15(13)20/h2-7,9-10H,8H2,1H3,(H3,21,25,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8497368 (2013) BindingDB Entry DOI: 10.7270/Q2KW5DN7
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM99211 (US8497368, 1 | US8497368, 17 | US8497368, 18) Show SMILES CC(=NNC(N)=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:2.2| Show InChI InChI=1S/C19H16FN7O/c1-11(24-25-19(21)28)16-4-5-18-23-10-14(27(18)26-16)8-13-7-12-3-2-6-22-17(12)9-15(13)20/h2-7,9-10H,8H2,1H3,(H3,21,25,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8497368 (2013) BindingDB Entry DOI: 10.7270/Q2KW5DN7
					More data for this Ligand-Target Pair