BDBM99218 US8497368, 8

SMILES: CN(N=C(C)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1)C(N)=O

InChI Key: InChIKey=XTJLRYYBZQMAFB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99218   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM99218 (US8497368, 8) Show SMILES CN(N=C(C)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1)C(N)=O |w:2.1| Show InChI InChI=1S/C20H18FN7O/c1-12(25-27(2)20(22)29)17-5-6-19-24-11-15(28(19)26-17)9-14-8-13-4-3-7-23-18(13)10-16(14)21/h3-8,10-11H,9H2,1-2H3,(H2,22,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8497368 (2013) BindingDB Entry DOI: 10.7270/Q2KW5DN7
					More data for this Ligand-Target Pair