BDBM99228 US8497368, 20

SMILES: CC(=NNC(N)=O)c1ccc2ncc(Cc3c(F)cc4ncccc4c3F)n2n1

InChI Key: InChIKey=RPSDNGJPBQUTLC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM99228 (US8497368, 20) Show SMILES CC(=NNC(N)=O)c1ccc2ncc(Cc3c(F)cc4ncccc4c3F)n2n1 |w:2.2| Show InChI InChI=1S/C19H15F2N7O/c1-10(25-26-19(22)29)15-4-5-17-24-9-11(28(17)27-15)7-13-14(20)8-16-12(18(13)21)3-2-6-23-16/h2-6,8-9H,7H2,1H3,(H3,22,26,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8497368 (2013) BindingDB Entry DOI: 10.7270/Q2KW5DN7
					More data for this Ligand-Target Pair