BDBM99254 US8497368, 46

SMILES: C[C@H](c1nnc2ccc(nn12)C(C)=NNC(N)=O)c1ccc2ncccc2c1

InChI Key: InChIKey=SPQNZMVPLNKJOR-NSHDSACASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM99254 (US8497368, 46) Show SMILES C[C@H](c1nnc2ccc(nn12)C(C)=NNC(N)=O)c1ccc2ncccc2c1 |r,w:13.15| Show InChI InChI=1S/C19H18N8O/c1-11(13-5-6-16-14(10-13)4-3-9-21-16)18-24-23-17-8-7-15(26-27(17)18)12(2)22-25-19(20)28/h3-11H,1-2H3,(H3,20,25,28)/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8497368 (2013) BindingDB Entry DOI: 10.7270/Q2KW5DN7
					More data for this Ligand-Target Pair