BDBM99257 US8497368, 49

SMILES: CC(c1nnc2ccc(nn12)C(C)=NNC(N)=O)c1c(F)cc2ncccc2c1F

InChI Key: InChIKey=CSHZVESOAIYXSL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99257   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM99257 (US8497368, 49) Show SMILES CC(c1nnc2ccc(nn12)C(C)=NNC(N)=O)c1c(F)cc2ncccc2c1F |w:13.15| Show InChI InChI=1S/C19H16F2N8O/c1-9(16-12(20)8-14-11(17(16)21)4-3-7-23-14)18-26-25-15-6-5-13(28-29(15)18)10(2)24-27-19(22)30/h3-9H,1-2H3,(H3,22,27,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8497368 (2013) BindingDB Entry DOI: 10.7270/Q2KW5DN7
					More data for this Ligand-Target Pair