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BDBM99268 US8497368, 60

SMILES: CN(N=C(C)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1)C(N)=O

InChI Key: InChIKey=BODSPDYFDMSKOO-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99268   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM99268
PNG
(US8497368, 60)
Show SMILES CN(N=C(C)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1)C(N)=O |w:2.1|
Show InChI InChI=1S/C18H17N9O/c1-11(24-26(2)18(19)28)15-9-21-16-17(22-15)27(25-23-16)10-12-5-6-14-13(8-12)4-3-7-20-14/h3-9H,10H2,1-2H3,(H2,19,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 0.800n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...


US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair