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BDBM99273 US8497368, 65

SMILES: NC(=O)NNC(=N)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1

InChI Key: InChIKey=QVCYTJJTTCUAKG-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99273   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM99273
PNG
(US8497368, 65)
Show SMILES NC(=O)NNC(=N)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1
Show InChI InChI=1S/C16H14N10O/c17-13(22-24-16(18)27)12-7-20-14-15(21-12)26(25-23-14)8-9-3-4-11-10(6-9)2-1-5-19-11/h1-7H,8H2,(H2,17,22)(H3,18,24,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 0.200n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...


US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair