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SMILES: COC(=O)NN=C(C)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1

InChI Key: InChIKey=IHDCXAAYKPVJBE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99282   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99282
PNG
(US8497368, 74)
Show SMILES COC(=O)NN=C(C)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1 |w:5.4|
Show InChI InChI=1S/C18H15FN8O2/c1-10(23-25-18(28)29-2)15-8-21-16-17(22-15)27(26-24-16)9-12-6-11-4-3-5-20-14(11)7-13(12)19/h3-8H,9H2,1-2H3,(H,25,28)
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KEGG

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Similars
US Patent
n/an/a 1n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair