null
SMILES: CC(=NNC(=O)c1ccncc1)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1
InChI Key: InChIKey=GQNZUYWKSKMQKI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM99283 (US8497368, 75) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-... | US Patent US8497368 (2013) BindingDB Entry DOI: 10.7270/Q2KW5DN7 | |||||||||||
More data for this Ligand-Target Pair |