BDBM99474 US8501768, 2

SMILES: FC(F)(F)Oc1ccc(cc1)N1CC[C@H]2CN(C[C@H]2C1=O)C(=O)Cc1ccccc1

InChI Key: InChIKey=HTXFDSBQYUYZIF-QFBILLFUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (Homo sapiens (Human))	BDBM99474 (US8501768, 2) Show SMILES FC(F)(F)Oc1ccc(cc1)N1CC[C@H]2CN(C[C@H]2C1=O)C(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C22H21F3N2O3/c23-22(24,25)30-18-8-6-17(7-9-18)27-11-10-16-13-26(14-19(16)21(27)29)20(28)12-15-4-2-1-3-5-15/h1-9,16,19H,10-14H2/t16-,19+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	49.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HSL enzyme activity was measured by a colorimetric assay.				US Patent US8501768 (2013) BindingDB Entry DOI: 10.7270/Q26Q1VW3
					More data for this Ligand-Target Pair