BDBM99478 US8501768, 6

SMILES: Fc1ccc(CN2C[C@@H]3CCN(C(=O)[C@@H]3C2)c2ccc(OC(F)(F)F)cc2)cc1

InChI Key: InChIKey=DXVHIIDHQSBIDF-HNAYVOBHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (Homo sapiens (Human))	BDBM99478 (US8501768, 6) Show SMILES Fc1ccc(CN2C[C@@H]3CCN(C(=O)[C@@H]3C2)c2ccc(OC(F)(F)F)cc2)cc1 |r| Show InChI InChI=1S/C21H20F4N2O2/c22-16-3-1-14(2-4-16)11-26-12-15-9-10-27(20(28)19(15)13-26)17-5-7-18(8-6-17)29-21(23,24)25/h1-8,15,19H,9-13H2/t15-,19+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	359	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HSL enzyme activity was measured by a colorimetric assay.				US Patent US8501768 (2013) BindingDB Entry DOI: 10.7270/Q26Q1VW3
					More data for this Ligand-Target Pair