BDBM99480 US8501768, 8

SMILES: CC(C)c1ccc(cc1)C(=O)N1C[C@@H]2CCN(C(=O)[C@@H]2C1)c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=UVQXTGZXMGDYMH-GHTZIAJQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99480   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (HSL) (Homo sapiens (Human))	BDBM99480 (US8501768, 8) Show SMILES CC(C)c1ccc(cc1)C(=O)N1C[C@@H]2CCN(C(=O)[C@@H]2C1)c1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C24H25F3N2O3/c1-15(2)16-3-5-17(6-4-16)22(30)28-13-18-11-12-29(23(31)21(18)14-28)19-7-9-20(10-8-19)32-24(25,26)27/h3-10,15,18,21H,11-14H2,1-2H3/t18-,21+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HSL enzyme activity was measured by a colorimetric assay.				US Patent US8501768 (2013) BindingDB Entry DOI: 10.7270/Q26Q1VW3
					More data for this Ligand-Target Pair