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SMILES: FC(F)(F)Oc1ccc(cc1)N1CC[C@H]2CN(C[C@H]2C1=O)S(=O)(=O)c1ccccc1Cl

InChI Key: InChIKey=IOHFWOZJENTFLA-XJKSGUPXSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99483   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hormone-sensitive lipase


(Homo sapiens (Human))		BDBM99483
PNG
(US8501768, 11)
Show SMILES FC(F)(F)Oc1ccc(cc1)N1CC[C@H]2CN(C[C@H]2C1=O)S(=O)(=O)c1ccccc1Cl |r|
Show InChI InChI=1S/C20H18ClF3N2O4S/c21-17-3-1-2-4-18(17)31(28,29)25-11-13-9-10-26(19(27)16(13)12-25)14-5-7-15(8-6-14)30-20(22,23)24/h1-8,13,16H,9-12H2/t13-,16+/m0/s1
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Similars
US Patent
n/an/a 50.1n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
HSL enzyme activity was measured by a colorimetric assay.

US Patent US8501768 (2013)


BindingDB Entry DOI: 10.7270/Q26Q1VW3
More data for this
Ligand-Target Pair