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SMILES: FC(F)(F)COc1ccc(cc1)N1CC[C@@H]2CN(C[C@@H]2C1=O)S(=O)(=O)c1cccnc1Cl

InChI Key: InChIKey=URZPTRWITOLAHH-CJNGLKHVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99487   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hormone-sensitive lipase


(Homo sapiens (Human))		BDBM99487
PNG
(US8501768, 15)
Show SMILES FC(F)(F)COc1ccc(cc1)N1CC[C@@H]2CN(C[C@@H]2C1=O)S(=O)(=O)c1cccnc1Cl |r|
Show InChI InChI=1S/C20H19ClF3N3O4S/c21-18-17(2-1-8-25-18)32(29,30)26-10-13-7-9-27(19(28)16(13)11-26)14-3-5-15(6-4-14)31-12-20(22,23)24/h1-6,8,13,16H,7,9-12H2/t13-,16+/m1/s1
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Similars
US Patent
n/an/a 727n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
HSL enzyme activity was measured by a colorimetric assay.

US Patent US8501768 (2013)


BindingDB Entry DOI: 10.7270/Q26Q1VW3
More data for this
Ligand-Target Pair