BindingDB logo
myBDB logout

null

SMILES: CCc1ccc(cc1)N1C[C@H]2CN(C[C@H]2C1=O)C(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=BVXPXCFIGDWPIB-DNVCBOLYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99501   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hormone-sensitive lipase


(Homo sapiens (Human))		BDBM99501
PNG
(US8501768, 29)
Show SMILES CCc1ccc(cc1)N1C[C@H]2CN(C[C@H]2C1=O)C(=O)Nc1ccc(OC(F)(F)F)cc1 |r|
Show InChI InChI=1S/C22H22F3N3O3/c1-2-14-3-7-17(8-4-14)28-12-15-11-27(13-19(15)20(28)29)21(30)26-16-5-9-18(10-6-16)31-22(23,24)25/h3-10,15,19H,2,11-13H2,1H3,(H,26,30)/t15-,19-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 637n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
HSL enzyme activity was measured by a colorimetric assay.

US Patent US8501768 (2013)


BindingDB Entry DOI: 10.7270/Q26Q1VW3
More data for this
Ligand-Target Pair