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SMILES: CCCCOC[C@]1(O)C[C@H]2CN(C(=O)[C@H]2C1)c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=ICURKDZAOKAZKG-OWQGQXMQSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99508   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hormone-sensitive lipase


(Homo sapiens (Human))		BDBM99508
PNG
(US8501768, 36)
Show SMILES CCCCOC[C@]1(O)C[C@H]2CN(C(=O)[C@H]2C1)c1ccc(OC(F)(F)F)cc1 |r|
Show InChI InChI=1S/C19H24F3NO4/c1-2-3-8-26-12-18(25)9-13-11-23(17(24)16(13)10-18)14-4-6-15(7-5-14)27-19(20,21)22/h4-7,13,16,25H,2-3,8-12H2,1H3/t13-,16-,18-/m0/s1
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Similars
US Patent
n/an/a 139n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
HSL enzyme activity was measured by a colorimetric assay.

US Patent US8501768 (2013)


BindingDB Entry DOI: 10.7270/Q26Q1VW3
More data for this
Ligand-Target Pair