null

SMILES: CS(=O)(=O)c1ccc(cc1)-c1cccc2nc(Nc3ccc(cc3)N3CCOCC3)nn12

InChI Key: InChIKey=RYAAAOAVTHIWNS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 99516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM99516 (US8501936, 12) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cccc2nc(Nc3ccc(cc3)N3CCOCC3)nn12 Show InChI InChI=1S/C23H23N5O3S/c1-32(29,30)20-11-5-17(6-12-20)21-3-2-4-22-25-23(26-28(21)22)24-18-7-9-19(10-8-18)27-13-15-31-16-14-27/h2-12H,13-16H2,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	434	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. US Patent					Assay Description The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...				US Patent US8501936 (2013) BindingDB Entry DOI: 10.7270/Q22Z1455
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM99516 (US8501936, 12) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cccc2nc(Nc3ccc(cc3)N3CCOCC3)nn12 Show InChI InChI=1S/C23H23N5O3S/c1-32(29,30)20-11-5-17(6-12-20)21-3-2-4-22-25-23(26-28(21)22)24-18-7-9-19(10-8-18)27-13-15-31-16-14-27/h2-12H,13-16H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17.7	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. US Patent					Assay Description The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...				US Patent US8501936 (2013) BindingDB Entry DOI: 10.7270/Q22Z1455
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM99516 (US8501936, 12) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cccc2nc(Nc3ccc(cc3)N3CCOCC3)nn12 Show InChI InChI=1S/C23H23N5O3S/c1-32(29,30)20-11-5-17(6-12-20)21-3-2-4-22-25-23(26-28(21)22)24-18-7-9-19(10-8-18)27-13-15-31-16-14-27/h2-12H,13-16H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. US Patent					Assay Description The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...				US Patent US8501936 (2013) BindingDB Entry DOI: 10.7270/Q22Z1455
					More data for this Ligand-Target Pair