BDBM99536 US8501936, 34

SMILES: COc1ccc(Nc2nc3c(cccn3n2)C2=CCN(CC2)S(C)(=O)=O)cc1

InChI Key: InChIKey=STGHZPGFCOXZTG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 99536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM99536 (US8501936, 34) Show SMILES COc1ccc(Nc2nc3c(cccn3n2)C2=CCN(CC2)S(C)(=O)=O)cc1 |t:18| Show InChI InChI=1S/C19H21N5O3S/c1-27-16-7-5-15(6-8-16)20-19-21-18-17(4-3-11-24(18)22-19)14-9-12-23(13-10-14)28(2,25)26/h3-9,11H,10,12-13H2,1-2H3,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. US Patent					Assay Description The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...				US Patent US8501936 (2013) BindingDB Entry DOI: 10.7270/Q22Z1455
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM99536 (US8501936, 34) Show SMILES COc1ccc(Nc2nc3c(cccn3n2)C2=CCN(CC2)S(C)(=O)=O)cc1 |t:18| Show InChI InChI=1S/C19H21N5O3S/c1-27-16-7-5-15(6-8-16)20-19-21-18-17(4-3-11-24(18)22-19)14-9-12-23(13-10-14)28(2,25)26/h3-9,11H,10,12-13H2,1-2H3,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. US Patent					Assay Description The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...				US Patent US8501936 (2013) BindingDB Entry DOI: 10.7270/Q22Z1455
					More data for this Ligand-Target Pair