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Enter Data

BDBM50222414 BML-210::CHEBI:61077::CHEMBL324053

SMILES: Nc1ccccc1NC(=O)CCCCCCC(=O)Nc1ccccc1

InChI Key: InChIKey=RFLHBLWLFUFFDZ-UHFFFAOYSA-N

Data: 4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50222414
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50222414 (BML-210 \| CHEBI:61077 \| CHEMBL324053) Show SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222414 (BML-210 \| CHEBI:61077 \| CHEMBL324053) Show SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cell extract by fluorescence plate reader assay				Nat Chem Biol 2: 551-8 (2006) Article DOI: 10.1038/nchembio815 BindingDB Entry DOI: 10.7270/Q29C718V
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222414 (BML-210 \| CHEBI:61077 \| CHEMBL324053) Show SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Inhibitory concentration against human histone deacetylase				J Med Chem 48: 1019-32 (2005) Article DOI: 10.1021/jm049207j BindingDB Entry DOI: 10.7270/Q25T3P70
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222414 (BML-210 \| CHEBI:61077 \| CHEMBL324053) Show SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extract				Bioorg Med Chem Lett 14: 3313-7 (2004) BindingDB Entry DOI: 10.7270/Q28054SZ
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair