BDBM50060257 3,3-Dimethyl-2,3-dihydro-indole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide::BRL-46470::CHEMBL285999
SMILES: CN1C2CCC1CC(C2)NC(=O)N1CC(C)(C)c2ccccc12
InChI Key: InChIKey=ILXWRFDRNAKTDD-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM50060257![]() (3,3-Dimethyl-2,3-dihydro-indole-1-carboxylic acid ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia& Upjohn Curated by ChEMBL | Assay Description In vitro affinity for 5-hydroxytryptamine 3 (5-HT3) receptor by displacement of [3H]BRL-43694 from rat entorhinal cortex | J Med Chem 40: 3369-80 (1997) Article DOI: 10.1021/jm970060o BindingDB Entry DOI: 10.7270/Q2X63NNK | |||||||||||
More data for this Ligand-Target Pair |