BDBM36425 CID25105702::N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-4-vinylbenzamide, 53

SMILES: C=Cc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O

InChI Key: InChIKey=RXEMEYIKURNJLE-UHFFFAOYSA-N

Data: 3 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 36425   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36425 (CID25105702 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[...) Show SMILES C=Cc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C23H26N4O2/c1-2-17-7-9-18(10-8-17)22(28)24-13-16-26-14-11-19(12-15-26)27-21-6-4-3-5-20(21)25-23(27)29/h2-10,19H,1,11-16H2,(H,24,28)(H,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description PLD in vitro enzymatic assay using phospholipase D1(PLD1).				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36425 (CID25105702 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[...) Show SMILES C=Cc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C23H26N4O2/c1-2-17-7-9-18(10-8-17)22(28)24-13-16-26-14-11-19(12-15-26)27-21-6-4-3-5-20(21)25-23(27)29/h2-10,19H,1,11-16H2,(H,24,28)(H,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description PLD in vitro enzymatic assay using phospholipase D2(PLD2).				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36425 (CID25105702 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[...) Show SMILES C=Cc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C23H26N4O2/c1-2-17-7-9-18(10-8-17)22(28)24-13-16-26-14-11-19(12-15-26)27-21-6-4-3-5-20(21)25-23(27)29/h2-10,19H,1,11-16H2,(H,24,28)(H,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	37
Vanderbilt University					Assay Description cell-based assay using HEK293-gfpPLD2 cell line				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36425 (CID25105702 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[...) Show SMILES C=Cc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C23H26N4O2/c1-2-17-7-9-18(10-8-17)22(28)24-13-16-26-14-11-19(12-15-26)27-21-6-4-3-5-20(21)25-23(27)29/h2-10,19H,1,11-16H2,(H,24,28)(H,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	79	n/a	n/a	n/a	37
Vanderbilt University					Assay Description cell-based assay using human non-small-cell lung cancer cell line, Calu-1				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36425 (CID25105702 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[...) Show SMILES C=Cc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C23H26N4O2/c1-2-17-7-9-18(10-8-17)22(28)24-13-16-26-14-11-19(12-15-26)27-21-6-4-3-5-20(21)25-23(27)29/h2-10,19H,1,11-16H2,(H,24,28)(H,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair