BDBM36415 4,5-Dibromo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)furan-2-carboxamide, 64::CID25105710

SMILES: Brc1cc(oc1Br)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O

InChI Key: InChIKey=FQFFYVYBFUVPGG-UHFFFAOYSA-N

Data: 3 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 36415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36415 (4,5-Dibromo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]...) Show SMILES Brc1cc(oc1Br)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C19H20Br2N4O3/c20-13-11-16(28-17(13)21)18(26)22-7-10-24-8-5-12(6-9-24)25-15-4-2-1-3-14(15)23-19(25)27/h1-4,11-12H,5-10H2,(H,22,26)(H,23,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description PLD in vitro enzymatic assay using phospholipase D1(PLD1).				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36415 (4,5-Dibromo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]...) Show SMILES Brc1cc(oc1Br)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C19H20Br2N4O3/c20-13-11-16(28-17(13)21)18(26)22-7-10-24-8-5-12(6-9-24)25-15-4-2-1-3-14(15)23-19(25)27/h1-4,11-12H,5-10H2,(H,22,26)(H,23,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description PLD in vitro enzymatic assay using phospholipase D2(PLD2).				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36415 (4,5-Dibromo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]...) Show SMILES Brc1cc(oc1Br)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C19H20Br2N4O3/c20-13-11-16(28-17(13)21)18(26)22-7-10-24-8-5-12(6-9-24)25-15-4-2-1-3-14(15)23-19(25)27/h1-4,11-12H,5-10H2,(H,22,26)(H,23,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	37
Vanderbilt University					Assay Description cell-based assay using HEK293-gfpPLD2 cell line				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36415 (4,5-Dibromo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]...) Show SMILES Brc1cc(oc1Br)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C19H20Br2N4O3/c20-13-11-16(28-17(13)21)18(26)22-7-10-24-8-5-12(6-9-24)25-15-4-2-1-3-14(15)23-19(25)27/h1-4,11-12H,5-10H2,(H,22,26)(H,23,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.90	n/a	n/a	n/a	37
Vanderbilt University					Assay Description cell-based assay using human non-small-cell lung cancer cell line, Calu-1				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM36415 (4,5-Dibromo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]...) Show SMILES Brc1cc(oc1Br)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C19H20Br2N4O3/c20-13-11-16(28-17(13)21)18(26)22-7-10-24-8-5-12(6-9-24)25-15-4-2-1-3-14(15)23-19(25)27/h1-4,11-12H,5-10H2,(H,22,26)(H,23,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair