BDBM50003579 CHEMBL3234889

SMILES: Cc1ccnc(Nc2sc(cc2C(N)=O)-c2ccccc2)c1

InChI Key: InChIKey=VTXTZOSQVPMRAU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003579   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50003579 (CHEMBL3234889) Show SMILES Cc1ccnc(Nc2sc(cc2C(N)=O)-c2ccccc2)c1 Show InChI InChI=1S/C17H15N3OS/c1-11-7-8-19-15(9-11)20-17-13(16(18)21)10-14(22-17)12-5-3-2-4-6-12/h2-10H,1H3,(H2,18,21)(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Bioorg Med Chem Lett 24: 1968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.02.064 BindingDB Entry DOI: 10.7270/Q2CF9RM3
					More data for this Ligand-Target Pair