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SMILES: COCCNC(=O)c1ccc(Cl)c(c1)-c1ccc2N(CCCc2c1)C(=O)c1c(F)cccc1Cl

InChI Key: InChIKey=AIWBYXKXIDKBKU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108907   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50108907
PNG
(CHEMBL3596606)
Show SMILES COCCNC(=O)c1ccc(Cl)c(c1)-c1ccc2N(CCCc2c1)C(=O)c1c(F)cccc1Cl
Show InChI InChI=1S/C26H23Cl2FN2O3/c1-34-13-11-30-25(32)18-7-9-20(27)19(15-18)16-8-10-23-17(14-16)4-3-12-31(23)26(33)24-21(28)5-2-6-22(24)29/h2,5-10,14-15H,3-4,11-13H2,1H3,(H,30,32)
PDB

UniProtKB/SwissProt

antibodypedia
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PC sid
UniChem

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PubMed
n/an/a 1.34E+3n/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...

Bioorg Med Chem Lett 25: 2991-7 (2015)


BindingDB Entry DOI: 10.7270/Q2ZP47XQ
More data for this
Ligand-Target Pair