BDBM50087117 CHEMBL3426594

SMILES: COc1ccc(cc1OC)-c1c(C)nn2c(NCCNC(C)=O)cc(C)nc12

InChI Key: InChIKey=FZPVOGSJCDLHJM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50087117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4-kinase type 2-alpha (Homo sapiens (Human))	BDBM50087117 (CHEMBL3426594) Show SMILES COc1ccc(cc1OC)-c1c(C)nn2c(NCCNC(C)=O)cc(C)nc12 Show InChI InChI=1S/C20H25N5O3/c1-12-10-18(22-9-8-21-14(3)26)25-20(23-12)19(13(2)24-25)15-6-7-16(27-4)17(11-15)28-5/h6-7,10-11,22H,8-9H2,1-5H3,(H,21,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Inhibition of PI4K2alpha (unknown origin) assessed as hydrolysis of ATP for 60 mins by ADP-Glo kinase assay				J Med Chem 58: 3767-93 (2015) Article DOI: 10.1021/acs.jmedchem.5b00499 BindingDB Entry DOI: 10.7270/Q2MW2JVR
					More data for this Ligand-Target Pair