BDBM119883 E144-0828

SMILES: CN(Cc1ccccc1)C(=O)CN(C)S(=O)(=O)c1cc(Br)cnc1N

InChI Key: InChIKey=AGTVYPXLTFYLPM-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119883   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrolipoyl dehydrogenase (Lpd) (Mycobacterium tuberculosis)	BDBM119883 (E144-0828) Show SMILES CN(Cc1ccccc1)C(=O)CN(C)S(=O)(=O)c1cc(Br)cnc1N Show InChI InChI=1S/C16H19BrN4O3S/c1-20(10-12-6-4-3-5-7-12)15(22)11-21(2)25(23,24)14-8-13(17)9-19-16(14)18/h3-9H,10-11H2,1-2H3,(H2,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College					Assay Description IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...				Biochemistry 52: 9375-84 (2013) Article DOI: 10.1021/bi401077f BindingDB Entry DOI: 10.7270/Q29K48X6
					More data for this Ligand-Target Pair