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SMILES: O=C(C1CC1)N1CCNCC1

InChI Key: InChIKey=KIALFUYSJAAJSU-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50498042   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Homo sapiens (Human))
BDBM50498042
PNG
(CHEMBL3329525)
Show SMILES O=C(C1CC1)N1CCNCC1
Show InChI InChI=1S/C8H14N2O/c11-8(7-1-2-7)10-5-3-9-4-6-10/h7,9H,1-6H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
6.00E+3n/an/an/an/an/an/an/an/a



Targacept, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H] nicotine from human alpha4beta2 nAChR transfected in SH-EP1 cells by liquid scintillation counting


Eur J Med Chem 86: 60-74 (2014)


Article DOI: 10.1016/j.ejmech.2014.08.019
BindingDB Entry DOI: 10.7270/Q2PK0K4H
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-2/beta-3


(Homo sapiens (Human))
BDBM50498042
PNG
(CHEMBL3329525)
Show SMILES O=C(C1CC1)N1CCNCC1
Show InChI InChI=1S/C8H14N2O/c11-8(7-1-2-7)10-5-3-9-4-6-10/h7,9H,1-6H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
2.60E+4n/an/an/an/an/an/an/an/a



Targacept, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]epibatidine from human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells by liquid scintillation counting


Eur J Med Chem 86: 60-74 (2014)


Article DOI: 10.1016/j.ejmech.2014.08.019
BindingDB Entry DOI: 10.7270/Q2PK0K4H
More data for this
Ligand-Target Pair