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SMILES: Oc1ccc2c(CSc3n[nH]c(=O)n3C3Cc4ccccc4C3)cc(=O)oc2c1

InChI Key: InChIKey=GFFMZZDAEHTERW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156769   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
NAD-dependent protein deacetylase sirtuin-2


(Homo sapiens (Human))		BDBM50156769
PNG
(4-((4-(2,3-dihydro-1H-inden-2-yl)-5-hydroxy-4H-1,2...)
Show SMILES Oc1ccc2c(CSc3n[nH]c(=O)n3C3Cc4ccccc4C3)cc(=O)oc2c1
Show InChI InChI=1S/C21H17N3O4S/c25-16-5-6-17-14(9-19(26)28-18(17)10-16)11-29-21-23-22-20(27)24(21)15-7-12-3-1-2-4-13(12)8-15/h1-6,9-10,15,25H,7-8,11H2,(H,22,27)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+5n/an/an/an/an/an/a



University of Kuopio

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assay

J Med Chem 47: 6292-8 (2004)


Article DOI: 10.1021/jm049933m
BindingDB Entry DOI: 10.7270/Q2S1820Z
More data for this
Ligand-Target Pair