BDBM212437 JMV 3011

SMILES: COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)c(OC)c1

InChI Key:

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 212437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM212437 (JMV 3011) Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)c(OC)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier 1					Assay Description Briefly, direct ligand binding experiments were performed using fluorescence energy transfer with the purified receptor labeled with Alexa Fluor 350 ...				J Biol Chem 288: 24656-65 (2013) Article DOI: 10.1074/jbc.M113.453423 BindingDB Entry DOI: 10.7270/Q2F18XKT
					More data for this Ligand-Target Pair
Ghrelin receptor 1a (GHS-R1a E124Q) (Homo sapiens (Human))	BDBM212437 (JMV 3011) Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)c(OC)c1 Show InChI	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	915	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier 1					Assay Description Briefly, direct ligand binding experiments were performed using fluorescence energy transfer with the purified receptor labeled with Alexa Fluor 350 ...				J Biol Chem 288: 24656-65 (2013) Article DOI: 10.1074/jbc.M113.453423 BindingDB Entry DOI: 10.7270/Q2F18XKT
					More data for this Ligand-Target Pair