BDBM50150854 6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-oxoethylamino)ethylamino)nicotinonitrile::6-{2-[2-(5-Cyano-4,5-dihydro-pyrazol-1-yl)-2-oxo-ethylamino]-ethylamino}-nicotinonitrile::CHEMBL184651::KR-62436

SMILES: O=C(CNCCNc1ccc(cn1)C#N)N1N=CCC1C#N

InChI Key: InChIKey=XNYVGGJJENHRBZ-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50150854   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase IV (Sus scrofa (pig))	BDBM50150854 (6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...) Show SMILES O=C(CNCCNc1ccc(cn1)C#N)N1N=CCC1C#N |c:17| Show InChI InChI=1S/C14H15N7O/c15-7-11-1-2-13(19-9-11)18-6-5-17-10-14(22)21-12(8-16)3-4-20-21/h1-2,4,9,12,17H,3,5-6,10H2,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibitory concentration against dipeptidyl peptidase IV of porcine kidney				Bioorg Med Chem Lett 14: 4461-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.046 BindingDB Entry DOI: 10.7270/Q2J9674N
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50150854 (6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...) Show SMILES O=C(CNCCNc1ccc(cn1)C#N)N1N=CCC1C#N |c:17| Show InChI InChI=1S/C14H15N7O/c15-7-11-1-2-13(19-9-11)18-6-5-17-10-14(22)21-12(8-16)3-4-20-21/h1-2,4,9,12,17H,3,5-6,10H2,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibitory concentration against dipeptidyl peptidase IV in Caco-2 cell assay				Bioorg Med Chem Lett 14: 4461-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.046 BindingDB Entry DOI: 10.7270/Q2J9674N
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50150854 (6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...) Show SMILES O=C(CNCCNc1ccc(cn1)C#N)N1N=CCC1C#N |c:17| Show InChI InChI=1S/C14H15N7O/c15-7-11-1-2-13(19-9-11)18-6-5-17-10-14(22)21-12(8-16)3-4-20-21/h1-2,4,9,12,17H,3,5-6,10H2,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Matrix Laboratories Limited Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem 17: 1783-802 (2009) Article DOI: 10.1016/j.bmc.2009.01.061 BindingDB Entry DOI: 10.7270/Q2VD70DJ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase IV (Rattus norvegicus (rat))	BDBM50150854 (6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...) Show SMILES O=C(CNCCNc1ccc(cn1)C#N)N1N=CCC1C#N |c:17| Show InChI InChI=1S/C14H15N7O/c15-7-11-1-2-13(19-9-11)18-6-5-17-10-14(22)21-12(8-16)3-4-20-21/h1-2,4,9,12,17H,3,5-6,10H2,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Matrix Laboratories Limited Curated by ChEMBL					Assay Description Inhibition of DPP4 in rat plasma				Bioorg Med Chem 17: 1783-802 (2009) Article DOI: 10.1016/j.bmc.2009.01.061 BindingDB Entry DOI: 10.7270/Q2VD70DJ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase IV (Sus scrofa (pig))	BDBM50150854 (6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...) Show SMILES O=C(CNCCNc1ccc(cn1)C#N)N1N=CCC1C#N |c:17| Show InChI InChI=1S/C14H15N7O/c15-7-11-1-2-13(19-9-11)18-6-5-17-10-14(22)21-12(8-16)3-4-20-21/h1-2,4,9,12,17H,3,5-6,10H2,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Matrix Laboratories Limited Curated by ChEMBL					Assay Description Inhibition of pig kidney DPP4				Bioorg Med Chem 17: 1783-802 (2009) Article DOI: 10.1016/j.bmc.2009.01.061 BindingDB Entry DOI: 10.7270/Q2VD70DJ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase IV (Rattus norvegicus (rat))	BDBM50150854 (6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...) Show SMILES O=C(CNCCNc1ccc(cn1)C#N)N1N=CCC1C#N |c:17| Show InChI InChI=1S/C14H15N7O/c15-7-11-1-2-13(19-9-11)18-6-5-17-10-14(22)21-12(8-16)3-4-20-21/h1-2,4,9,12,17H,3,5-6,10H2,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibitory concentration against rat dipeptidyl peptidase IV				Bioorg Med Chem Lett 14: 4461-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.046 BindingDB Entry DOI: 10.7270/Q2J9674N
					More data for this Ligand-Target Pair