BDBM62217 2,4-dimethyl-6-[2-oxidanylidene-2-(4-phenylpiperazin-1-yl)ethyl]-1,6-naphthyridin-5-one::2,4-dimethyl-6-[2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]-1,6-naphthyridin-5-one::2,4-dimethyl-6-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-1,6-naphthyridin-5-one::6-[2-keto-2-(4-phenylpiperazino)ethyl]-2,4-dimethyl-1,6-naphthyridin-5-one::KUC103672N::cid_44473128

SMILES: Cc1cc(C)c2c(ccn(CC(=O)N3CCN(CC3)c3ccccc3)c2=O)n1

InChI Key: InChIKey=QCKTXJMYYWWSQN-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 62217   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
regulator of G-protein signaling 4 (Homo sapiens (Human))	BDBM62217 (2,4-dimethyl-6-[2-oxidanylidene-2-(4-phenylpiperaz...) Show SMILES Cc1cc(C)c2c(ccn(CC(=O)N3CCN(CC3)c3ccccc3)c2=O)n1 Show InChI InChI=1S/C22H24N4O2/c1-16-14-17(2)23-19-8-9-26(22(28)21(16)19)15-20(27)25-12-10-24(11-13-25)18-6-4-3-5-7-18/h3-9,14H,10-13,15H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CF9NJZ
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM62217 (2,4-dimethyl-6-[2-oxidanylidene-2-(4-phenylpiperaz...) Show SMILES Cc1cc(C)c2c(ccn(CC(=O)N3CCN(CC3)c3ccccc3)c2=O)n1 Show InChI InChI=1S/C22H24N4O2/c1-16-14-17(2)23-19-8-9-26(22(28)21(16)19)15-20(27)25-12-10-24(11-13-25)18-6-4-3-5-7-18/h3-9,14H,10-13,15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2M043TQ
					More data for this Ligand-Target Pair
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM62217 (2,4-dimethyl-6-[2-oxidanylidene-2-(4-phenylpiperaz...) Show SMILES Cc1cc(C)c2c(ccn(CC(=O)N3CCN(CC3)c3ccccc3)c2=O)n1 Show InChI InChI=1S/C22H24N4O2/c1-16-14-17(2)23-19-8-9-26(22(28)21(16)19)15-20(27)25-12-10-24(11-13-25)18-6-4-3-5-7-18/h3-9,14H,10-13,15H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2VH5M8G
					More data for this Ligand-Target Pair
RGS7 (Homo sapiens (Human))	BDBM62217 (2,4-dimethyl-6-[2-oxidanylidene-2-(4-phenylpiperaz...) Show SMILES Cc1cc(C)c2c(ccn(CC(=O)N3CCN(CC3)c3ccccc3)c2=O)n1 Show InChI InChI=1S/C22H24N4O2/c1-16-14-17(2)23-19-8-9-26(22(28)21(16)19)15-20(27)25-12-10-24(11-13-25)18-6-4-3-5-7-18/h3-9,14H,10-13,15H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2416VG3
					More data for this Ligand-Target Pair