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BDBM50052028 7-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]-8-propyl-chroman-2-carboxylic acid::CHEMBL90788::LY-247826

SMILES: CCCc1c(OCCCOc2cc(O)c(cc2CC)C(C)=O)ccc2CCC(Oc12)C(O)=O

InChI Key: InChIKey=XVOIIUGMYVACGS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052028   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leukotriene B4 receptor


(Homo sapiens (Human))		BDBM50052028
PNG
(7-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(cc2CC)C(C)=O)ccc2CCC(Oc12)C(O)=O
Show InChI InChI=1S/C26H32O7/c1-4-7-19-22(10-8-18-9-11-23(26(29)30)33-25(18)19)31-12-6-13-32-24-15-21(28)20(16(3)27)14-17(24)5-2/h8,10,14-15,23,28H,4-7,9,11-13H2,1-3H3,(H,29,30)
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Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for inhibitory activity against human neutrophil LTB4 receptor binding

J Med Chem 39: 2629-54 (1996)


Article DOI: 10.1021/jm960088k
BindingDB Entry DOI: 10.7270/Q21J9BFT
More data for this
Ligand-Target Pair