BDBM50252323 (R)-2-Methoxyaporphin-11-yl pentanoate::CHEMBL482276::MCL-516::R(-)-2-methoxy-11-valeryloxy-N-n-propylnoraporhine

SMILES: CCCCC(=O)Oc1cccc2C[C@H]3N(C)CCc4cc(OC)cc(c34)-c12

InChI Key: InChIKey=NMUGDOOOAXACRK-LJQANCHMSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50252323   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50252323 ((R)-2-Methoxyaporphin-11-yl pentanoate | CHEMBL482...) Show SMILES CCCCC(=O)Oc1cccc2C[C@H]3N(C)CCc4cc(OC)cc(c34)-c12 |r| Show InChI InChI=1S/C23H27NO3/c1-4-5-9-21(25)27-20-8-6-7-15-13-19-22-16(10-11-24(19)2)12-17(26-3)14-18(22)23(15)20/h6-8,12,14,19H,4-5,9-11,13H2,1-3H3/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	116	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cells				Bioorg Med Chem 16: 6675-81 (2008) Article DOI: 10.1016/j.bmc.2008.05.077 BindingDB Entry DOI: 10.7270/Q2SB45KD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50252323 ((R)-2-Methoxyaporphin-11-yl pentanoate | CHEMBL482...) Show SMILES CCCCC(=O)Oc1cccc2C[C@H]3N(C)CCc4cc(OC)cc(c34)-c12 |r| Show InChI InChI=1S/C23H27NO3/c1-4-5-9-21(25)27-20-8-6-7-15-13-19-22-16(10-11-24(19)2)12-17(26-3)14-18(22)23(15)20/h6-8,12,14,19H,4-5,9-11,13H2,1-3H3/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	151	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat 5HT1A receptor expressed in CHO cells				Bioorg Med Chem 16: 6675-81 (2008) Article DOI: 10.1016/j.bmc.2008.05.077 BindingDB Entry DOI: 10.7270/Q2SB45KD
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50252323 ((R)-2-Methoxyaporphin-11-yl pentanoate | CHEMBL482...) Show SMILES CCCCC(=O)Oc1cccc2C[C@H]3N(C)CCc4cc(OC)cc(c34)-c12 |r| Show InChI InChI=1S/C23H27NO3/c1-4-5-9-21(25)27-20-8-6-7-15-13-19-22-16(10-11-24(19)2)12-17(26-3)14-18(22)23(15)20/h6-8,12,14,19H,4-5,9-11,13H2,1-3H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	192	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]nemonapride from dopamine D2 receptor in rat forebrain				Bioorg Med Chem Lett 19: 51-3 (2008) Article DOI: 10.1016/j.bmcl.2008.11.025 BindingDB Entry DOI: 10.7270/Q26W99XP
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50252323 ((R)-2-Methoxyaporphin-11-yl pentanoate | CHEMBL482...) Show SMILES CCCCC(=O)Oc1cccc2C[C@H]3N(C)CCc4cc(OC)cc(c34)-c12 |r| Show InChI InChI=1S/C23H27NO3/c1-4-5-9-21(25)27-20-8-6-7-15-13-19-22-16(10-11-24(19)2)12-17(26-3)14-18(22)23(15)20/h6-8,12,14,19H,4-5,9-11,13H2,1-3H3/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor in rat forebrain				Bioorg Med Chem Lett 19: 51-3 (2008) Article DOI: 10.1016/j.bmcl.2008.11.025 BindingDB Entry DOI: 10.7270/Q26W99XP
					More data for this Ligand-Target Pair