BDBM86476 NS1209::SPD 502

SMILES: CN(C)S(=O)(=O)c1ccc(cc1)-c1cc2=C(NOC(CCO)C(O)=O)C(=O)N=c2c2CN(C)CCc12

InChI Key: InChIKey=CFJRSKULEDUDKL-UHFFFAOYSA-N

Data: 7 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 86476   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GRIK1 (Homo sapiens (Human))	BDBM86476 (NS1209 | SPD 502) Show SMILES CN(C)S(=O)(=O)c1ccc(cc1)-c1cc2=C(NOC(CCO)C(O)=O)C(=O)N=c2c2CN(C)CCc12 |c:15,28| Show InChI InChI=1S/C24H28N4O7S/c1-27(2)36(33,34)15-6-4-14(5-7-15)17-12-18-21(19-13-28(3)10-8-16(17)19)25-23(30)22(18)26-35-20(9-11-29)24(31)32/h4-7,12,20,29H,8-11,13H2,1-3H3,(H,31,32)(H,25,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NeuroSearch A/S Curated by PDSP Ki Database									J Pharmacol Exp Ther 309: 1003-10 (2004) Article DOI: 10.1124/jpet.103.062794 BindingDB Entry DOI: 10.7270/Q2610XX3
					More data for this Ligand-Target Pair
GRIK1 (Homo sapiens (Human))	BDBM86476 (NS1209 | SPD 502) Show SMILES CN(C)S(=O)(=O)c1ccc(cc1)-c1cc2=C(NOC(CCO)C(O)=O)C(=O)N=c2c2CN(C)CCc12 |c:15,28| Show InChI InChI=1S/C24H28N4O7S/c1-27(2)36(33,34)15-6-4-14(5-7-15)17-12-18-21(19-13-28(3)10-8-16(17)19)25-23(30)22(18)26-35-20(9-11-29)24(31)32/h4-7,12,20,29H,8-11,13H2,1-3H3,(H,31,32)(H,25,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NeuroSearch A/S Curated by PDSP Ki Database									J Pharmacol Exp Ther 309: 1003-10 (2004) Article DOI: 10.1124/jpet.103.062794 BindingDB Entry DOI: 10.7270/Q2610XX3
					More data for this Ligand-Target Pair
GRIK1 (Homo sapiens (Human))	BDBM86476 (NS1209 | SPD 502) Show SMILES CN(C)S(=O)(=O)c1ccc(cc1)-c1cc2=C(NOC(CCO)C(O)=O)C(=O)N=c2c2CN(C)CCc12 |c:15,28| Show InChI InChI=1S/C24H28N4O7S/c1-27(2)36(33,34)15-6-4-14(5-7-15)17-12-18-21(19-13-28(3)10-8-16(17)19)25-23(30)22(18)26-35-20(9-11-29)24(31)32/h4-7,12,20,29H,8-11,13H2,1-3H3,(H,31,32)(H,25,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NeuroSearch A/S Curated by PDSP Ki Database									J Pharmacol Exp Ther 309: 1003-10 (2004) Article DOI: 10.1124/jpet.103.062794 BindingDB Entry DOI: 10.7270/Q2610XX3
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM86476 (NS1209 | SPD 502) Show SMILES CN(C)S(=O)(=O)c1ccc(cc1)-c1cc2=C(NOC(CCO)C(O)=O)C(=O)N=c2c2CN(C)CCc12 |c:15,28| Show InChI InChI=1S/C24H28N4O7S/c1-27(2)36(33,34)15-6-4-14(5-7-15)17-12-18-21(19-13-28(3)10-8-16(17)19)25-23(30)22(18)26-35-20(9-11-29)24(31)32/h4-7,12,20,29H,8-11,13H2,1-3H3,(H,31,32)(H,25,26,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NeuroSearch A/S Curated by PDSP Ki Database									J Pharmacol Exp Ther 309: 1003-10 (2004) Article DOI: 10.1124/jpet.103.062794 BindingDB Entry DOI: 10.7270/Q2610XX3
					More data for this Ligand-Target Pair
GRIK1 (Homo sapiens (Human))	BDBM86476 (NS1209 | SPD 502) Show SMILES CN(C)S(=O)(=O)c1ccc(cc1)-c1cc2=C(NOC(CCO)C(O)=O)C(=O)N=c2c2CN(C)CCc12 |c:15,28| Show InChI InChI=1S/C24H28N4O7S/c1-27(2)36(33,34)15-6-4-14(5-7-15)17-12-18-21(19-13-28(3)10-8-16(17)19)25-23(30)22(18)26-35-20(9-11-29)24(31)32/h4-7,12,20,29H,8-11,13H2,1-3H3,(H,31,32)(H,25,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NeuroSearch A/S Curated by PDSP Ki Database									J Pharmacol Exp Ther 309: 1003-10 (2004) Article DOI: 10.1124/jpet.103.062794 BindingDB Entry DOI: 10.7270/Q2610XX3
					More data for this Ligand-Target Pair
GRIK1 (Homo sapiens (Human))	BDBM86476 (NS1209 | SPD 502) Show SMILES CN(C)S(=O)(=O)c1ccc(cc1)-c1cc2=C(NOC(CCO)C(O)=O)C(=O)N=c2c2CN(C)CCc12 |c:15,28| Show InChI InChI=1S/C24H28N4O7S/c1-27(2)36(33,34)15-6-4-14(5-7-15)17-12-18-21(19-13-28(3)10-8-16(17)19)25-23(30)22(18)26-35-20(9-11-29)24(31)32/h4-7,12,20,29H,8-11,13H2,1-3H3,(H,31,32)(H,25,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NeuroSearch A/S Curated by PDSP Ki Database									J Pharmacol Exp Ther 309: 1003-10 (2004) Article DOI: 10.1124/jpet.103.062794 BindingDB Entry DOI: 10.7270/Q2610XX3
					More data for this Ligand-Target Pair
GRIK1 (Homo sapiens (Human))	BDBM86476 (NS1209 | SPD 502) Show SMILES CN(C)S(=O)(=O)c1ccc(cc1)-c1cc2=C(NOC(CCO)C(O)=O)C(=O)N=c2c2CN(C)CCc12 |c:15,28| Show InChI InChI=1S/C24H28N4O7S/c1-27(2)36(33,34)15-6-4-14(5-7-15)17-12-18-21(19-13-28(3)10-8-16(17)19)25-23(30)22(18)26-35-20(9-11-29)24(31)32/h4-7,12,20,29H,8-11,13H2,1-3H3,(H,31,32)(H,25,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NeuroSearch A/S Curated by PDSP Ki Database									J Pharmacol Exp Ther 309: 1003-10 (2004) Article DOI: 10.1124/jpet.103.062794 BindingDB Entry DOI: 10.7270/Q2610XX3
					More data for this Ligand-Target Pair