BDBM50014888 4-Benzoylamino-4-dipropylcarbamoyl-butyric acid::CHEMBL316561::Proglumide

SMILES: CCCN(CCC)C(=O)C(CCC(O)=O)NC(=O)c1ccccc1

InChI Key: InChIKey=DGMKFQYCZXERLX-UHFFFAOYSA-N

Data: 1 KI  5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50014888   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin (RAT)	BDBM50014888 (4-Benzoylamino-4-dipropylcarbamoyl-butyric acid | ...) Show SMILES CCCN(CCC)C(=O)C(CCC(O)=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C18H26N2O4/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 83: 4918-22 (1986) Article DOI: 10.1073/pnas.83.13.4918 BindingDB Entry DOI: 10.7270/Q2445K05
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50014888 (4-Benzoylamino-4-dipropylcarbamoyl-butyric acid | ...) Show SMILES CCCN(CCC)C(=O)C(CCC(O)=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C18H26N2O4/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]gastrin to Cholecystokinin type B receptor from guinea pig gastric glands				J Med Chem 33: 591-5 (1990) BindingDB Entry DOI: 10.7270/Q29K4BTP
					More data for this Ligand-Target Pair
Histamine H2 receptor (RAT)	BDBM50014888 (4-Benzoylamino-4-dipropylcarbamoyl-butyric acid | ...) Show SMILES CCCN(CCC)C(=O)C(CCC(O)=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C18H26N2O4/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against binding of [125I](Nle11)-HG-13 to Histamine H2 receptor in vitro				J Med Chem 28: 273-8 (1985) BindingDB Entry DOI: 10.7270/Q2ST7QC9
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50014888 (4-Benzoylamino-4-dipropylcarbamoyl-butyric acid | ...) Show SMILES CCCN(CCC)C(=O)C(CCC(O)=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C18H26N2O4/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]- CCK-33 to rat pancreas				J Med Chem 33: 591-5 (1990) BindingDB Entry DOI: 10.7270/Q29K4BTP
					More data for this Ligand-Target Pair
Cholecystokinin A receptor (Cavia porcellus)	BDBM50014888 (4-Benzoylamino-4-dipropylcarbamoyl-butyric acid | ...) Show SMILES CCCN(CCC)C(=O)C(CCC(O)=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C18H26N2O4/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]- CCK-33 to guinea pig cortex				J Med Chem 33: 591-5 (1990) BindingDB Entry DOI: 10.7270/Q29K4BTP
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50014888 (4-Benzoylamino-4-dipropylcarbamoyl-butyric acid | ...) Show SMILES CCCN(CCC)C(=O)C(CCC(O)=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C18H26N2O4/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity for binding of [125I]-(Nle11)-HG-13 to gastrin receptor on isolated rabbit gastric mucosal cells.				J Med Chem 30: 758-63 (1987) BindingDB Entry DOI: 10.7270/Q2CV4GRT
					More data for this Ligand-Target Pair