BDBM50409062 CHEMBL143022::QF-1003B
SMILES: Fc1ccc(cc1)C(=O)C1CCN(CC2Cc3occc3C(=O)C2)CC1
InChI Key: InChIKey=XFBPGUPMMWBWAS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50409062![]() (CHEMBL143022 | QF-1003B) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 52.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Antagonist activity at human cloned 5HT2A receptor | J Med Chem 51: 6085-94 (2008) Article DOI: 10.1021/jm800602w BindingDB Entry DOI: 10.7270/Q2571D72 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50409062![]() (CHEMBL143022 | QF-1003B) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 95.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from human cloned 5HT2A receptor | J Med Chem 51: 6085-94 (2008) Article DOI: 10.1021/jm800602w BindingDB Entry DOI: 10.7270/Q2571D72 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50409062![]() (CHEMBL143022 | QF-1003B) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 151 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from human cloned dopamine D2 receptor | J Med Chem 51: 6085-94 (2008) Article DOI: 10.1021/jm800602w BindingDB Entry DOI: 10.7270/Q2571D72 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50409062![]() (CHEMBL143022 | QF-1003B) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine from human cloned 5HT2C receptor | J Med Chem 51: 6085-94 (2008) Article DOI: 10.1021/jm800602w BindingDB Entry DOI: 10.7270/Q2571D72 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2b (5HT2A and 5HT2B) (RAT) | BDBM50409062![]() (CHEMBL143022 | QF-1003B) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 195 | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundus | J Med Chem 45: 54-71 (2001) BindingDB Entry DOI: 10.7270/Q2KD204K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2b (5HT2A and 5HT2B) (RAT) | BDBM50409062![]() (CHEMBL143022 | QF-1003B) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 195 | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago Curated by ChEMBL | Assay Description Compound was evaluated for antagonism against serotonin (5-hydroxytryptamine 2B receptor) receptor | J Med Chem 43: 4678-93 (2001) BindingDB Entry DOI: 10.7270/Q24B32H0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50409062![]() (CHEMBL143022 | QF-1003B) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 52.5 | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aorta | J Med Chem 45: 54-71 (2001) BindingDB Entry DOI: 10.7270/Q2KD204K | |||||||||||
More data for this Ligand-Target Pair |