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BDBM75003 9-methyl-N-(6-methyl-2-pyridinyl)-4H-thieno[3,2-c][1]benzopyran-2-carboxamide::9-methyl-N-(6-methyl-2-pyridyl)-4H-thieno[3,2-c]chromene-2-carboxamide::9-methyl-N-(6-methylpyridin-2-yl)-4H-thieno[3,2-c]chromene-2-carboxamide::MLS000731527::SMR000309802::cid_16194088

SMILES: Cc1cccc(NC(=O)c2cc3COc4cccc(C)c4-c3s2)n1

InChI Key: InChIKey=FJDIANMSTKKRQR-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75003   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens (Human))
BDBM75003
PNG
(9-methyl-N-(6-methyl-2-pyridinyl)-4H-thieno[3,2-c]...)
Show SMILES Cc1cccc(NC(=O)c2cc3COc4cccc(C)c4-c3s2)n1
Show InChI InChI=1S/C19H16N2O2S/c1-11-5-3-7-14-17(11)18-13(10-23-14)9-15(24-18)19(22)21-16-8-4-6-12(2)20-16/h3-9H,10H2,1-2H3,(H,20,21,22)
PDB
MMDB

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Similars

PCBioAssay
n/an/an/an/a 7.29E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair