BDBM88805 MLS002179739::N-(5-chloranylpyridin-2-yl)-2-[(5,6-dimethyl-4-oxidanylidene-3H-thieno[2,3-d]pyrimidin-2-yl)methylsulfanyl]propanamide::N-(5-chloro-2-pyridinyl)-2-[(5,6-dimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)methylthio]propanamide::N-(5-chloro-2-pyridyl)-2-[(4-keto-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-2-yl)methylthio]propionamide::N-(5-chloropyridin-2-yl)-2-[(5,6-dimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)methylsulfanyl]propanamide::SMR001268769::cid_25162023

SMILES: CC(SCc1nc2sc(C)c(C)c2c(=O)[nH]1)C(=O)Nc1ccc(Cl)cn1

InChI Key: InChIKey=JBTJXFQJJLRXKC-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 88805   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
tyrosine-protein phosphatase non-receptor type 5 isoform a (Homo sapiens (Human))	BDBM88805 (MLS002179739 | N-(5-chloranylpyridin-2-yl)-2-[(5,6...) Show SMILES CC(SCc1nc2sc(C)c(C)c2c(=O)[nH]1)C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C17H17ClN4O2S2/c1-8-9(2)26-17-14(8)16(24)21-13(22-17)7-25-10(3)15(23)20-12-5-4-11(18)6-19-12/h4-6,10H,7H2,1-3H3,(H,19,20,23)(H,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2DV1HGT
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM88805 (MLS002179739 | N-(5-chloranylpyridin-2-yl)-2-[(5,6...) Show SMILES CC(SCc1nc2sc(C)c(C)c2c(=O)[nH]1)C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C17H17ClN4O2S2/c1-8-9(2)26-17-14(8)16(24)21-13(22-17)7-25-10(3)15(23)20-12-5-4-11(18)6-19-12/h4-6,10H,7H2,1-3H3,(H,19,20,23)(H,21,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	927	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2959G44
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM88805 (MLS002179739 | N-(5-chloranylpyridin-2-yl)-2-[(5,6...) Show SMILES CC(SCc1nc2sc(C)c(C)c2c(=O)[nH]1)C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C17H17ClN4O2S2/c1-8-9(2)26-17-14(8)16(24)21-13(22-17)7-25-10(3)15(23)20-12-5-4-11(18)6-19-12/h4-6,10H,7H2,1-3H3,(H,19,20,23)(H,21,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2FQ9V6B
					More data for this Ligand-Target Pair
tyrosine-protein phosphatase non-receptor type 5 isoform a (Homo sapiens (Human))	BDBM88805 (MLS002179739 | N-(5-chloranylpyridin-2-yl)-2-[(5,6...) Show SMILES CC(SCc1nc2sc(C)c(C)c2c(=O)[nH]1)C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C17H17ClN4O2S2/c1-8-9(2)26-17-14(8)16(24)21-13(22-17)7-25-10(3)15(23)20-12-5-4-11(18)6-19-12/h4-6,10H,7H2,1-3H3,(H,19,20,23)(H,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	3.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2KH0KWR
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM88805 (MLS002179739 | N-(5-chloranylpyridin-2-yl)-2-[(5,6...) Show SMILES CC(SCc1nc2sc(C)c(C)c2c(=O)[nH]1)C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C17H17ClN4O2S2/c1-8-9(2)26-17-14(8)16(24)21-13(22-17)7-25-10(3)15(23)20-12-5-4-11(18)6-19-12/h4-6,10H,7H2,1-3H3,(H,19,20,23)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	5.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2T43RPN
					More data for this Ligand-Target Pair