BindingDB logo
myBDB logout

null

SMILES: CSCc1cc(\C=C2/C(=O)Nc3ccccc23)cc(CSC)c1O

InChI Key: InChIKey=HXAVERUVVZQIGE-SXGWCWSVSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292508   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50292508
PNG
(3-(4-hydroxy-3,5-bis(methylthiomethyl)benzylidene)...)
Show SMILES CSCc1cc(\C=C2/C(=O)Nc3ccccc23)cc(CSC)c1O
Show InChI InChI=1S/C19H19NO2S2/c1-23-10-13-7-12(8-14(11-24-2)18(13)21)9-16-15-5-3-4-6-17(15)20-19(16)22/h3-9,21H,10-11H2,1-2H3,(H,20,22)/b16-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 400n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of EGFR in human A431 cells

J Nat Prod 55: 1529-1560 (1992)


Article DOI: 10.1021/np50089a001
BindingDB Entry DOI: 10.7270/Q2J966CC
More data for this
Ligand-Target Pair