BDBM50004927 4-Phosphonomethyl-piperidine-2-carboxylic acid::4-Phosphonomethyl-piperidine-2-carboxylic acid (CGS-19755, LY 272541)::CGS 19755::CGS-19755::CHEMBL39664::Selfotel::cis-(+)-((2S,4R)-4-Phosphonomethyl-piperidine-2-carboxylic acid

SMILES: OC(=O)[C@@H]1C[C@H](CP(O)(O)=O)CCN1

InChI Key: InChIKey=LPMRCCNDNGONCD-RITPCOANSA-N

Data: 4 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50004927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50004927 (4-Phosphonomethyl-piperidine-2-carboxylic acid | 4...) Show SMILES OC(=O)[C@@H]1C[C@H](CP(O)(O)=O)CCN1 Show InChI InChI=1S/C7H14NO5P/c9-7(10)6-3-5(1-2-8-6)4-14(11,12)13/h5-6,8H,1-4H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by PDSP Ki Database									Br J Pharmacol 95: 932-8 (1988) Article DOI: 10.1111/j.1476-5381.1988.tb11723.x BindingDB Entry DOI: 10.7270/Q2Z036NF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50004927 (4-Phosphonomethyl-piperidine-2-carboxylic acid | 4...) Show SMILES OC(=O)[C@@H]1C[C@H](CP(O)(O)=O)CCN1 Show InChI InChI=1S/C7H14NO5P/c9-7(10)6-3-5(1-2-8-6)4-14(11,12)13/h5-6,8H,1-4H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 310: 563-70 (2004) Article DOI: 10.1124/jpet.104.066092 BindingDB Entry DOI: 10.7270/Q2DJ5D6D
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50004927 (4-Phosphonomethyl-piperidine-2-carboxylic acid | 4...) Show SMILES OC(=O)[C@@H]1C[C@H](CP(O)(O)=O)CCN1 Show InChI InChI=1S/C7H14NO5P/c9-7(10)6-3-5(1-2-8-6)4-14(11,12)13/h5-6,8H,1-4H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merrell Dow Research Institute Curated by ChEMBL					Assay Description Binding affinity towards AMPA receptor using [3H]AMPA as radioligand; Inactive				J Med Chem 33: 2961-3 (1990) BindingDB Entry DOI: 10.7270/Q2BK1CXM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate (Rattus norvegicus)	BDBM50004927 (4-Phosphonomethyl-piperidine-2-carboxylic acid | 4...) Show SMILES OC(=O)[C@@H]1C[C@H](CP(O)(O)=O)CCN1 Show InChI InChI=1S/C7H14NO5P/c9-7(10)6-3-5(1-2-8-6)4-14(11,12)13/h5-6,8H,1-4H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merrell Dow Research Institute Curated by ChEMBL					Assay Description Binding affinity towards Ionotropic glutamate receptor kainate using [3H]-kainic acid as radioligand; Inactive				J Med Chem 33: 2961-3 (1990) BindingDB Entry DOI: 10.7270/Q2BK1CXM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50004927 (4-Phosphonomethyl-piperidine-2-carboxylic acid | 4...) Show SMILES OC(=O)[C@@H]1C[C@H](CP(O)(O)=O)CCN1 Show InChI InChI=1S/C7H14NO5P/c9-7(10)6-3-5(1-2-8-6)4-14(11,12)13/h5-6,8H,1-4H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	967	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Carlo Bo Curated by ChEMBL					Assay Description Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA				J Med Chem 48: 6887-96 (2005) Article DOI: 10.1021/jm058018d BindingDB Entry DOI: 10.7270/Q28C9X1X
					More data for this Ligand-Target Pair
NMDA receptor subunit N2A (GluN2A) (Rattus norvegicus (Rat))	BDBM50004927 (4-Phosphonomethyl-piperidine-2-carboxylic acid | 4...) Show SMILES OC(=O)[C@@H]1C[C@H](CP(O)(O)=O)CCN1 Show InChI InChI=1S/C7H14NO5P/c9-7(10)6-3-5(1-2-8-6)4-14(11,12)13/h5-6,8H,1-4H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of [3H]Glu binding to rat N-methyl-D-aspartic acid receptor 2A				J Med Chem 48: 5489-94 (2005) Article DOI: 10.1021/jm050174x BindingDB Entry DOI: 10.7270/Q2HD7WFN
					More data for this Ligand-Target Pair
NMDA receptor subunit N2A (GluN2A) (Rattus norvegicus (Rat))	BDBM50004927 (4-Phosphonomethyl-piperidine-2-carboxylic acid | 4...) Show SMILES OC(=O)[C@@H]1C[C@H](CP(O)(O)=O)CCN1 Show InChI InChI=1S/C7H14NO5P/c9-7(10)6-3-5(1-2-8-6)4-14(11,12)13/h5-6,8H,1-4H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of [3H]CPP binding to rat N-methyl-D-aspartic acid receptor 2A				J Med Chem 48: 5489-94 (2005) Article DOI: 10.1021/jm050174x BindingDB Entry DOI: 10.7270/Q2HD7WFN
					More data for this Ligand-Target Pair