BDBM50321026 CHEMBL4172984

SMILES: OC(=O)CNC(=O)c1c(O)c2CCCCc2n(Cc2ccc(cc2)C(F)(F)F)c1=O

InChI Key: InChIKey=ZWUICGDUBQOGNC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321026   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50321026 (CHEMBL4172984) Show SMILES OC(=O)CNC(=O)c1c(O)c2CCCCc2n(Cc2ccc(cc2)C(F)(F)F)c1=O Show InChI InChI=1S/C20H19F3N2O5/c21-20(22,23)12-7-5-11(6-8-12)10-25-14-4-2-1-3-13(14)17(28)16(19(25)30)18(29)24-9-15(26)27/h5-8,28H,1-4,9-10H2,(H,24,29)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Cadila Healthcare Limited Curated by ChEMBL					Assay Description Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...				J Med Chem 61: 6964-6982 (2018) Article DOI: 10.1021/acs.jmedchem.7b01686 BindingDB Entry DOI: 10.7270/Q2H70JC7
					More data for this Ligand-Target Pair