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SMILES: O=C(Nc1cccc(c1)-c1ccccc1)Oc1cccc(c1)-c1ccccc1

InChI Key: InChIKey=GJGNAZXEUGJLTC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271028   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50271028
PNG
(Biphenyl-3-ylcarbamic Acid Biphenyl-3-yl Ester | C...)
Show SMILES O=C(Nc1cccc(c1)-c1ccccc1)Oc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C25H19NO2/c27-25(26-23-15-7-13-21(17-23)19-9-3-1-4-10-19)28-24-16-8-14-22(18-24)20-11-5-2-6-12-20/h1-18H,(H,26,27)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.09E+3n/an/an/an/an/an/a



Università degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain membrane assessed as [3H]anandamide hydrolysis


J Med Chem 51: 3487-98 (2008)


Article DOI: 10.1021/jm701631z
BindingDB Entry DOI: 10.7270/Q2TM79W9
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))
BDBM50271028
PNG
(Biphenyl-3-ylcarbamic Acid Biphenyl-3-yl Ester | C...)
Show SMILES O=C(Nc1cccc(c1)-c1ccccc1)Oc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C25H19NO2/c27-25(26-23-15-7-13-21(17-23)19-9-3-1-4-10-19)28-24-16-8-14-22(18-24)20-11-5-2-6-12-20/h1-18H,(H,26,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair