null
SMILES: O=C(Nc1cccc(c1)-c1ccccc1)Oc1cccc(c1)-c1ccccc1
InChI Key: InChIKey=GJGNAZXEUGJLTC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM50271028![]() (Biphenyl-3-ylcarbamic Acid Biphenyl-3-yl Ester | C...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of FAAH in rat brain membrane assessed as [3H]anandamide hydrolysis | J Med Chem 51: 3487-98 (2008) Article DOI: 10.1021/jm701631z BindingDB Entry DOI: 10.7270/Q2TM79W9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Rattus norvegicus (Rat)) | BDBM50271028![]() (Biphenyl-3-ylcarbamic Acid Biphenyl-3-yl Ester | C...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | 8.0 | n/a |
University of California, Irvine | Assay Description The measurement of the ability of URB602 compound to inhibit MGL activity. | Chem Biol 14: 1357-65 (2007) Article DOI: 10.1016/j.chembiol.2007.10.017 BindingDB Entry DOI: 10.7270/Q2XS5SW0 | |||||||||||
More data for this Ligand-Target Pair |